Research progress on follicle-stimulating hormone and its receptor in menopausal women / 中华老年医学杂志

ABSTRACT

Menopause leads to significant changes in serum levels of reproductive hormones and increased incidences of menopause-related diseases.Because of the impact of follicle-stimulating hormone(FSH)and its receptor(FSHR)on women's physical and mental health and quality of life, research has been conducted and progress has been made concerning their involvement in the pathogenesis of osteoporosis, abnormal lipid metabolism, cardiovascular disease, cancer, cognitive impairment and other disorders, thus laying the foundation for an understanding of the molecular mechanisms underlying the development of these postmenopausal diseases.