Progress and perspective of gene therapy / 药学实践杂志

ABSTRACT

Gene therapy is generally referred as a therapeutic method through modifying or manipulating gene expression and accordingly changing biological characteristics of living cells. With the substantial progress of vector delivery, gene editing and other relevant technologies, gene therapy has been widely applied in the research of genetic disorder, cancer and other refractory diseases. Gene therapy products have been approved in many countries and exhibited amazing therapeutic effectiveness. Big pharmaceutical companies have strategically entered this field along with many innovative entrepreneurs. Gene therapy has showed great market potential and prospect. In this review, research progresses, industrial developments, administration policies, as well as future expectations of the gene therapy were discussed.