Invasive Fungal Sinusitis of the Sphenoid Sinus
Clinical and Experimental Otorhinolaryngology
;
: 181-187, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-93547
ABSTRACT
OBJECTIVE:
This study was conducted to present the clinical outcome of invasive fungal sinusitis of the sphenoid sinus and to analyze clinical factors influencing patient survival.METHODS:
A retrospective review of 12 cases of invasive fungal sphenoiditis was conducted.RESULTS:
Cases were divided into acute fulminant invasive fungal spheonoidits (n=4) and chronic invasive fungal sphenoiditis (n=8). The most common underlying disease was diabetes mellitus (n=9). The most common presenting symptoms and signs included visual disturbance (100%). Intracranial extension was observed in 8 patients. Endoscopic debridement and intravenous antifungals were given to all patients. Fatal aneurysmal rupture of the internal carotid artery occurred suddenly in two patients. The mortality rate was 100% for patients with acute fulminant invasive fungal sphenoiditis and 25% for patients with chronic invasive fungal sphenoiditis. In survival analysis, intracranial extension was evaluated as a statistically significant factor (P=0.027).CONCLUSION:
The survival rate of chronic invasive fungal sphenoiditis was 75%. However, the prognosis of acute fulminant invasive fungal sphenoiditis was extremely poor despite the application of aggressive treatment, thus, a high index of suspicion should be required and new diagnostic markers need to be developed for early diagnosis of invasive fungal sinusitis of the sphenoid sinus.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Rotura
/
Sinusitis
/
Seno Esfenoidal
/
Arteria Carótida Interna
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Mortalidad
/
Desbridamiento
/
Diagnóstico Precoz
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Humanos
Idioma:
Inglés
Revista:
Clinical and Experimental Otorhinolaryngology
Año:
2014
Tipo del documento:
Artículo
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