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Research progress in biological characteristics and influencing factors of jaw bone marrow mesenchymal stem cell / 中华口腔医学杂志
Chinese Journal of Stomatology ; (12): 107-112, 2022.
Artículo en Chino | WPRIM | ID: wpr-935837
ABSTRACT
Jaw bone marrow mesenchymal stem cell (JBMMSC), which exists in the maxilla and mandible, is adult stem cells with strong proliferation ability and multiple differentiation potential. Pathological, physicochemical and biological factors can affect the biological characteristics of JBMMSC. Compared with bone marrow mesenchymal stem cells derived from long bone, the biological characteristics of JBMMSC are site-specific because of the different sources of tissue and osteogenesis of bone. The same influencing factors have different effects on these two kinds of cells. Besides, JBMMSC also has the advantages of easier access, less trauma and lower immunogenicity. It has broad application prospects in craniomaxillofacial defect repair, periodontal tissue regeneration, and improving the success rate after implantation and so on. It has attracted wide attention in the basic and clinical studies. However, the regulation mechanism of its proliferation and differentiation is not clear, which affects its application as seed cell. Therefore, this paper reviews the biological characteristics influencing factors of JBMMSC and application progress in clinical and basic research, aiming to provide reference for further research and clinical application.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Osteogénesis / Células de la Médula Ósea / Diferenciación Celular / Células Cultivadas / Células Madre Mesenquimatosas / Maxilar Idioma: Chino Revista: Chinese Journal of Stomatology Año: 2022 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Osteogénesis / Células de la Médula Ósea / Diferenciación Celular / Células Cultivadas / Células Madre Mesenquimatosas / Maxilar Idioma: Chino Revista: Chinese Journal of Stomatology Año: 2022 Tipo del documento: Artículo