Appropriate Use of Glycopeptide Antibiotics and Therapeutic Drug Monitoring for Invasive Infections / 대한내과학회지
Korean Journal of Medicine
;
: 463-477, 2021.
Artículo
en Coreano
| WPRIM
| ID: wpr-938646
ABSTRACT
Vancomycin and teicoplanin are representative glycopeptide antibiotics with activities against gram-positive cocci. The area under the drug concentration–time curve (AUC)/minimal inhibitory concentration (MIC) has been extensively used as an indicator of the bacteriological response to glycopeptide antibiotics, and the trough concentration has been used as a surrogate marker for the AUC/MIC. However, the guidelines for therapeutic drug monitoring (TDM) are being revised in accordance with increasing pharmacokinetic understanding of glycopeptide antibiotics. This review describes the pharmacokinetic/pharmacodynamic characteristics of glycopeptide antibiotics and discusses their optimal use with appropriate TDM.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Guía de Práctica Clínica
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2021
Tipo del documento:
Artículo
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