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Survival analysis of unexpected small cell lung cancer following surgery / 中华肿瘤杂志
Chinese Journal of Oncology ; (12): 550-554, 2022.
Artículo en Chino | WPRIM | ID: wpr-940921
ABSTRACT

Objective:

To investigate the survival and influencing factors of unexpected small cell lung cancer following surgery.

Methods:

We respectively reviewed the clinical characters of 104 patients who underwent surgical treatment and be proved as small cell lung cancer by pathology between January 2000 to October 2020 in Chinese PLA General Hospital. Overall survival (OS) of patients was evaluated using Kaplan-Meier and Cox proportional hazards analysis.

Results:

Of 104 patients, 27 cases showed central lesions, and other 77 showed peripheral nodules. The margin of nodules was smooth in 42 cases on CT imaging. The median OS was 34.3 months and 5-year OS rate was 45.8%. Postoperative 5-year OS rates for patients were 52.1%, 45.4%, and 27.8% for clinical stages Ⅰ, Ⅱ, and Ⅲ, respectively. Univariate analyses identified the age, surgical access, surgical approach, N stage, TNM stage and vascular cancer emboli were associated with OS (P<0.05). The N stage was an independent factor for the OS of patients (P<0.05).

Conclusions:

Patients with unexpected SCLC, including Ⅰ, Ⅱ and part ⅢA stage have favorable outcome and can benefit from surgery and systemic postoperative treatment. Standard lobectomy plus systemic lymph node dissection is commended.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Análisis de Supervivencia / Estudios Retrospectivos / Carcinoma Pulmonar de Células Pequeñas / Neoplasias Pulmonares / Escisión del Ganglio Linfático / Estadificación de Neoplasias Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Chino Revista: Chinese Journal of Oncology Año: 2022 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Análisis de Supervivencia / Estudios Retrospectivos / Carcinoma Pulmonar de Células Pequeñas / Neoplasias Pulmonares / Escisión del Ganglio Linfático / Estadificación de Neoplasias Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Chino Revista: Chinese Journal of Oncology Año: 2022 Tipo del documento: Artículo