The Association between Serum Uric Acid Level and Incidence of Metabolic Syndrome according to Menopausal Status in Korean Women
Journal of Menopausal Medicine
;
: 126-132, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-94108
ABSTRACT
OBJECTIVES:
The aim of this study is to investigate the association between serum uric acid level and metabolic syndrome according to menopausal status in Korean women.METHODS:
A total of 2,241 women who visited to the health promotion center at Pusan National University Hospital from 2010 to 2014 were included in this cross-sectional study. Self-report questionnaires and interviews with healthcare providers were used to assess disease history, medication history, menstrual history and body size measuring. Anthropometric measurements and laboratory results were compared as presence of metabolic syndrome and menopausal status by student-t test. Logistic regression analysis was performed between presence of metabolic syndrome and presumable predictive factors, such as age, menopause and serum uric acid.RESULTS:
The prevalence rate of metabolic syndrome were 7.45% (63/846) in pre-menopausal group and 23.87% (333/1395) in menopausal group. Serum uric acid level was higher in menopausal women than premenopausal women (4.6 +/- 1.1 vs. 4.3 +/- 0.9. P = 0.000). And, its concentration was also higher in metabolic syndrome than normal women regarding of menopausal statue (premenopause 4.7 +/- 1.1 vs. 4.2 +/- 0.8, P = 0.001, menopause 4.9 +/- 1.3 vs. 4.5 +/- 1.0, P = 0.000). Multiple logistic regression analysis showed serum uric acid and age have relationship with metabolic syndrome (OR 1.453, 95% confidence interval [CI] 1.074-1.111, P = 0.000; OR 1.092, 95% CI 1.305-1.619, P = 0.000).CONCLUSION:
We could find out some potential of uric acid as predictive factor for metabolic syndrome in premenopausal and menopausal group. Further investigation is required to clarify the relationship between serum uric acid, menopause and metabolic syndrome.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ácido Úrico
/
Menopausia
/
Modelos Logísticos
/
Incidencia
/
Prevalencia
/
Estudios Transversales
/
Encuestas y Cuestionarios
/
Personal de Salud
/
Síndrome Metabólico
/
Tamaño Corporal
Tipo de estudio:
Estudio de incidencia
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Journal of Menopausal Medicine
Año:
2014
Tipo del documento:
Artículo
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