Research progress of conversion therapy in colorectal cancer liver metastases / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 85-93, 2021.
Article
en Zh
| WPRIM
| ID: wpr-942869
Biblioteca responsable:
WPRO
ABSTRACT
The probability of developing liver metastases in patients with colorectal cancer is 40%-50%. Liver metastases remain an important adverse factor affecting long-term prognosis of colorectal cancer patients. Surgical resection of liver metastases is the only potentially curative treatment option. After comprehensive treatment, initially unresectable liver metastases might be converted to resectable tumors. This concept is known as conversion therapy. In this review, research status of conversion therapy in colorectal cancer liver metastases was summarized, providing updated concept of resectability, discussions on the assessment of tumor response and timing of operation, debates on the influence on tumor sidedness, and latest advancement in the treatment strategy of conversion therapy. Through analyzing existing problems, we hope to offer insights into possible progress in the future and provide references for the development of clinical practice.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Pronóstico
/
Neoplasias Colorrectales
/
Terapia Combinada
/
Investigación Biomédica
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Hepatectomía
/
Neoplasias Hepáticas
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Gastrointestinal Surgery
Año:
2021
Tipo del documento:
Article