Application of biomimetic nano drug delivery system of macrophage membrane in disease targeted therapy / 中国药房
China Pharmacy
;
(12): 2290-2294, 2022.
Artículo
en Chino
| WPRIM
| ID: wpr-943075
ABSTRACT
In recent years ,biomimetic nanodelivery system based on cell membrane coating has developed rapidly and shows better biocompatibility and efficacy than traditional nanodelivery systems in a variety of diseases . Macrophages,as members of the immune system ,are closely related to the occurrence and development of a variety of diseases . Macrophages are derived from monocytes and can be polarized into M 1 and M 2 types after corresponding stimulation : M1 macrophages involved in the proinflammatory reaction and M 2 macrophages involved in the inflammatory reaction . This paper reviews the application status of biomimetic nanoparticles coated with macrophage membrane in disease targeted therapy in recent years . Biomimetic nanoparticles coated with macrophage membrane has shown its high targeting and low immunogenicity in the treatment of malignant tumors (breast cancer ,colorectal cancer ,melanoma,glioma),Alzheimer’s disease ,liver ischemia -reperfusion injury ,atherosclerosis and so on . However,the research of Biomimetic nanoparticles coated with macrophage membrane currently focuses on anti -tumor research and is still in the laboratory research stage .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
China Pharmacy
Año:
2022
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS