Surface Characteristics and Biocompatibility of Micro Arc Oxidized Titanium Alloy / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
; : 9-17, 2015.
Article
en Ko
| WPRIM
| ID: wpr-94916
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: The aim of this research was to characterize micro arc oxidized titanium (MAO-Ti), accompanied by biocompatibility test in vivo as well as in vitro in comparison to the different types of surface modification; machined, blasted and plasma spray. MATERIALS AND METHODS: XRD and SEM investigations were performed in order to assess the structure and morphology. Biologic and morphologic responses to the osteoblast cell lines (Saos-2) were then examined, using Promeg(R) proliferation assay, alkalinephosphatase activity, alphavbeta3 integrin expression and cytoskeleton staining (Rhodamine-Phallodine). The analysis of gene expression for osteocalcin and collagen I was done through RT-PCR. RESULTS: MAO-Ti showed more activity on osteointegration and cell differentiation compared to other types of surface modification. CONCLUSION: In summary, MAO-Ti appears to exhibit more favorable biocompatibility than the compared groups in vitro and in vivo as well.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Osteoblastos
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Plasma
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Titanio
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Citoesqueleto
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Expresión Génica
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Osteocalcina
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Diferenciación Celular
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Línea Celular
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Colágeno
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Aleaciones
Idioma:
Ko
Revista:
Journal of Korean Orthopaedic Research Society
Año:
2015
Tipo del documento:
Article