Progress of immune cell reconstitution after allogeneic hematopoietic stem cell transplantation / 国际儿科学杂志

ABSTRACT

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective cure for many hematologic and non-hematologic diseases.However, infection morbidity and mortality remain high after allo-HSCT, which is closely related to the recovery of immune cell subsets.The detailed information on the recovery of natural killer(NK), T and B cell subsets can better predict and regulate the occurrence of adverse events.This article will review the current rules, influencing factors and the relationship between the outcome and the immune reconstitution of NK cells, T cells and B cells after hematopoietic stem cell transplantation.