Progress of C3 glomerulopathy / 国际儿科学杂志
International Journal of Pediatrics
; (6): 433-437, 2022.
Article
en Zh
| WPRIM
| ID: wpr-954053
Biblioteca responsable:
WPRO
ABSTRACT
C3 glomerulopathy is a rare disease of glomeruli mediated by abnormal activation of alternative complement pathway secondary to congenital genetic defects and acquired autoantibodies.Renal biopsy is the gold standard for diagnosing C3 glomerulopathy.C3 glomerulopathy encompasses both dense deposit disease and C3 glomerulonephritis.The main glomerular immunofluorescence staining is C3, with few or without immunoglobulins deposition, which is the obvious pathological feature.The clinical manifestations of C3 glomerulopathy are usually various, with limited detection methods and therapies and poor prognosis.This article mainly reviews the progress of C3 glomerulopathy in recent years, in order to improve clinical understanding of C3 glomerulopathy, and choose individualized therapy.
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Índice:
WPRIM
Idioma:
Zh
Revista:
International Journal of Pediatrics
Año:
2022
Tipo del documento:
Article