SLC7A11 and glioma / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 604-607, 2022.
Artículo
en Chino
| WPRIM
| ID: wpr-954331
ABSTRACT
Glioma is the most common primary brain tumor in adults and is essentially a polygenic abnormal disease. Solute carrier family 7 member 11 (SLC7A11) is a core component of the cystine/glutamate transporter and its expression is regulated at the transcriptional and translational levels. SLC7A11 mediates glioma cells proliferation, invasion and chemoradiotherapy resistance through regulation of oxidative stress and ferroptosis. Deep study of SLC7A11 will provide new theoretical basis and therapeutic targets for the treatment of gliomas.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of International Oncology
Año:
2022
Tipo del documento:
Artículo
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