Levosulpiride-induced Parkinsonim
Journal of the Korean Neurological Association
;
: 418-421, 2003.
Artículo
en Coreano
| WPRIM
| ID: wpr-95810
ABSTRACT
The present report discusses four cases of chronic renal failure, which developed symptoms of parkinsonism in response to levosulpiride. The temporal relationship between levosulpiride discontinuation and the disappearance of parkinsonism suggests a causal link. In addition, decreased striatal dopamine transporter bindings assessed by [I-123] IPT SPECT were observed in two patients suggesting that a dopamine blocking agent causes the dysfunction of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis of drug-induced parkinsonism.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Dopamina
/
Tomografía Computarizada de Emisión de Fotón Único
/
Trastornos Parkinsonianos
/
Proteínas de Transporte de Dopamina a través de la Membrana Plasmática
/
Neuronas Dopaminérgicas
/
Fallo Renal Crónico
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Año:
2003
Tipo del documento:
Artículo
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