Progress in cross reactivity of neutralizing monoclonal antibodies against dengue virus / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
; (12): 495-499, 2022.
Article
en Zh
| WPRIM
| ID: wpr-958217
Biblioteca responsable:
WPRO
ABSTRACT
Neutralizing monoclonal antibodies against dengue virus cross-react with other flaviviruses due to the sequence homology between them, such as the antibodies targeting envelope protein and non-structural protein 1. Apart from exerting protective effects in infected animals, cross-neutralizing antibodies could also cause antibody-dependent enhancement (ADE) in vivo. This review summarized the progress in cross-reactivity of neutralizing antibodies against dengue virus.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Microbiology and Immunology
Año:
2022
Tipo del documento:
Article