Neuromyelitis Optica (review) / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 939-940, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-959122
ABSTRACT
@# Neuromyelitis optica (NMO) is a rare demyelinating disease, affecting selectively optic nerve and spinal cord. NMO-IgG, an auto-antibody against aquaporin-4 (AQP4), identifies NMO as a disease entity separating from a severe variant of multiple sclerosis (MS). AQP4 is particularly abundant on the central nervous system, and is involves in regulation of water among of glial cells, and the blood and cerebrospinal fluid. NMO-IgG can target the AQP4 and initiate immune response leading to AQP4 protein loss in lesions, which is the key pathological mechanism of NMO.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Rehabilitation Theory and Practice
Año:
2012
Tipo del documento:
Artículo
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