Primary vaginal gestational trophoblastic neoplasia treated with uterine angiographic embolization and Etoposide, Methotrexate, Actinomycin D, Cyclophosphamide, and Vincristine: Philippines’ first reported case / Philippine Journal of Obstetrics and Gynecology
Philippine Journal of Obstetrics and Gynecology
;
: 177-181, 2022.
Artículo
en Inglés
| WPRIM
| ID: wpr-965017
ABSTRACT
@#Gestational trophoblastic neoplasia (GTN) in itself is an uncommon condition, much so is primary extrauterine GTN. The incidence of GTN in the Philippines is at 22.4/40,000 pregnancies. However, no report has been made for primary extrauterine GTN. Only two cases of primary vaginal choriocarcinoma are reported in literature. This is a case of a 26 year old G1P0 (0010) who came in for profuse vaginal bleeding. Serum beta‑human chorionic gonadotropin (β‑hCG) was elevated and ultrasound showed hypervascular vaginal mass and an empty uterus. A primary vaginal GTN was considered and the patient was treated with etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine (EMACO) regimen. During the course of chemotherapy, there was a note of profuse vaginal bleeding which was controlled by angiographic uterine artery embolization. A normal β‑hCG level was achieved after six cycles of EMACO. The patient was able to have three successful pregnancy outcomes thereafter. Primary vaginal GTN is a rare condition that requires a high index of suspicion. In a nulliparous patient complicated with profuse vaginal bleeding, angiographic embolization is an effective fertility‑sparing procedure that can manage the said complication.
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Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Embarazo Ectópico
/
Neoplasias Trofoblásticas
/
Embolización Terapéutica
Idioma:
Inglés
Revista:
Philippine Journal of Obstetrics and Gynecology
Año:
2022
Tipo del documento:
Artículo
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