Development of severe junctional bradycardia after dexmedetomidine infusion in a polypharmacy patient: a case report and literature review / 고신대학교의과대학학술지
Kosin Medical Journal
;
: 50-55, 2023.
Artículo
en Inglés
| WPRIM
| ID: wpr-968326
ABSTRACT
The authors report a case of newly manifested severe junctional bradycardia following dexmedetomidine administration during spinal anesthesia in a polypharmacy patient. A 77-year-old woman receiving multiple medications, including a beta-blocker and a calcium channel blocker, underwent right total knee arthroplasty. After spinal anesthesia, intravenous dexmedetomidine was initiated as a sedative; her heart rate decreased, followed by junctional bradycardia (heart rate, 37–41 beats/min). Dexmedetomidine was discontinued, and a dopamine infusion was initiated. Seven hours after surgery, junctional bradycardia persisted; a temporary transvenous pacemaker was inserted, and the beta-blocker and calcium channel blocker were discontinued. The patient was discharged on postoperative day 11 without any sequelae. Anesthesiologists should be aware of dexmedetomidine’s inhibitory effects on the cardiac conduction system, especially in geriatric patients taking medications with negative chronotropic effects and in combination with neuraxial anesthesia.
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Inglés
Revista:
Kosin Medical Journal
Año:
2023
Tipo del documento:
Artículo
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