Role of Th17 Cell and Autoimmunity in Chronic Obstructive Pulmonary Disease
Immune Network
;
: 109-114, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-96926
ABSTRACT
The molecular mechanisms involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) are poorly defined. Accumulating evidences indicate that chronic inflammatory responses and adaptive immunity play important roles in the development and progression of the disease. Recently, it has been shown that IL-17 producing CD4 T cells, named Th17 cells, which have been implicated in the pathogenesis of several inflammatory and autoimmune diseases, are involved in airway inflammation and COPD. In addition, we and others suggest that autoimmunity may play a critical role in the pathogenesis of COPD. Here, we will review the current understanding of roles of Th17 cells and autoimmune responses in COPD.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedades Autoinmunes
/
Linfocitos T
/
Autoinmunidad
/
Interleucina-17
/
Enfermedad Pulmonar Obstructiva Crónica
/
Inmunidad Adaptativa
/
Células Th17
/
Inflamación
Idioma:
Inglés
Revista:
Immune Network
Año:
2010
Tipo del documento:
Artículo
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