Cell-loaded hydrogel microspheres based on droplet microfluidics: a review / 生物工程学报
Chinese Journal of Biotechnology
; (12): 74-85, 2023.
Article
en Zh
| WPRIM
| ID: wpr-970360
Biblioteca responsable:
WPRO
ABSTRACT
Droplet microfluidics technology offers refined control over the flows of multiple fluids in micro/nano-scale, enabling fabrication of micro/nano-droplets with precisely adjustable structures and compositions in a high-throughput manner. With the combination of proper hydrogel materials and preparation methods, single or multiple cells can be efficiently encapsulated into hydrogels to produce cell-loaded hydrogel microspheres. The cell-loaded hydrogel microspheres can provide a three-dimensional, relatively independent and controllable microenvironment for cell proliferation and differentiation, which is of great value for three-dimensional cell culture, tissue engineering and regenerative medicine, stem cell research, single cell study and many other biological science fields. In this review, the preparation methods of cell-loaded hydrogel microspheres based on droplet microfluidics and its applications in biomedical field are summarized and future prospects are proposed.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Hidrogeles
/
Ingeniería de Tejidos
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Microfluídica
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Medicina Regenerativa
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Microesferas
Idioma:
Zh
Revista:
Chinese Journal of Biotechnology
Año:
2023
Tipo del documento:
Article