Recent studies on dilated cardiomyopathy caused by TTN mutations in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 217-222, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-971063
ABSTRACT
The mutations of TTN gene that encodes titin are the most common mutation type among the genetic causes of dilated cardiomyopathy (DCM). This article reviews the worldwide studies on potential molecular pathogenesis (transcription, post-translational modification, etc.), clinical phenotypes, and gene therapies of pediatric DCM caused by TTN mutations, with the hope of providing a reference for the precision treatment of pediatric DCM caused by TTN mutations.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Cardiomiopatía Dilatada
/
Terapia Genética
/
Conectina
/
Mutación
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2023
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS