Protective effect of decursin and decursinol angelate-rich Angelica gigas Nakai extract on dextran sulfate sodium-induced murine ulcerative colitis
Asian Pacific Journal of Tropical Medicine
; (12): 864-870, 2017.
Article
en Zh
| WPRIM
| ID: wpr-972562
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the anti-inflammatory effects of decursin and decursinol angelate-rich Angelica gigas Nakai (AGNE) on dextran sulfate sodium (DSS)-induced murine ulcerative colitis (UC). Methods The therapeutic effect of an AGNE was analyzed in a mouse model of UC induced by DSS. Disease activity index values were measured by clinical signs such as a weight loss, stool consistency, rectal bleeding and colon length. A histological analysis was performed using hematoxylin and eosin staining. Key inflammatory cytokines and mediators including IL-6, TNF-α PGE
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WPRIM
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Zh
Revista:
Asian Pacific Journal of Tropical Medicine
Año:
2017
Tipo del documento:
Article