In vitro, in vivo and in silico anti-hyperglycemic inhibition by sinigrin

Qamar ABBAS; Mubashir HASSAN; Hussain RAZA; Song-Ja KIM; Ki-Wha CHUNG; Gwang-Hoon KIM; Sung-Yum SEO

In vitro, in vivo and in silico anti-hyperglycemic inhibition by sinigrin

Qamar ABBAS; Mubashir HASSAN; Hussain RAZA; Song-Ja KIM; Ki-Wha CHUNG; Gwang-Hoon KIM; Sung-Yum SEO.

Asian Pacific Journal of Tropical Medicine ; (12): 372-379, 2017.

Artículo en Chino | WPRIM | ID: wpr-972641

ABSTRACT

ABSTRACT

Objective To evaluate the anti-hyperglycemic potential of sinigrin using in vitro, in silico and in vivo streptozotocin (STZ) induced hyperglycemic zebrafish model. Methods The in vitro enzyme inhibition assay was carried out to determine the IC

Anti-hyperglycemia; MD simulations; Sinigrin; Zebrafish; α-amylase; α-glucosidase

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Asian Pacific Journal of Tropical Medicine Año: 2017 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Asian Pacific Journal of Tropical Medicine Año: 2017 Tipo del documento: Artículo