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Changes of the ultrastructure of global cerebral ischemia and reperfusion damage in rats / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice ; (12): 8-10, 2006.
Artículo en Chino | WPRIM | ID: wpr-973501
ABSTRACT
@#ObjectiveTo investigate the changes of ultrastructure of global cerebral ischemia and reperfusion damage in rats.MethodsSix adult male Wistar rats were randomly divided into the ischemia group (n=3), and sham injury group (n=3). Global cerebral ischemia and reperfusion model were established with Pulsinelli's method. Cortical ultrastructure changes were investigated on the first hour after reperfusion.ResultsIn the ischemia group, different degrees of pyconosis neurons, abnormal organell and microtube of neurons were observed. In addition, glial cell and microvessels were damaged in ischemia group, but that in sham injury group were not demaged.ConclusionCortical neurons, neuroglia cells, cytoskeleton and blood-brain barrier changed at early stage of reperfusion damage.

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Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Rehabilitation Theory and Practice Año: 2006 Tipo del documento: Artículo

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Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Rehabilitation Theory and Practice Año: 2006 Tipo del documento: Artículo