Insulin-Derived Cutaneous Amyloidosis: A Possible Complication of Repeated Insulin Injections
Annals of Dermatology
;
: S71-S75, 2023.
Artículo
en Inglés
| WPRIM
| ID: wpr-976639
ABSTRACT
Primary localized cutaneous amyloidosis (PLCA) is characterized by extracellular deposition of pathological fibril aggregation of proteins in the skin without systemic involvement.Macular amyloidosis, lichen (papular) amyloidosis, and nodular amyloidosis are three different subtypes of PLCA. Although the pathological mechanism of PLCA has not yet been clarified, it is assumed that a nucleus formation of amyloid fibril is formed due to repeated external stimulation, such as subcutaneous injection, which often poses diagnostic challenges. Herein, we present a 54-year-old Korean male patient with cutaneous localized amyloidosis which occurred after repeated local insulin injections, and discuss the relationship between insulin therapy in patients with diabetes mellitus and dermal amyloid deposition.
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WPRIM (Pacífico Occidental)
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2023
Tipo del documento:
Artículo
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