Research progress on the development of human neutrophil elastase inhibitors / 药学学报
Acta Pharmaceutica Sinica
;
(12): 909-918, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-978760
ABSTRACT
Human neutrophil elastase (hNE) is a serine proteolytic enzyme mainly distributed in neutrophils. When the balance between anti-hNE protein and hNE is broken, excessive release of hNE can cause the occurrence of various diseases. Therefore, inhibition of hNE is a promising therapeutic strategy. In this paper, the structure, action mechanism, physiological function of hNE and the development of hNE inhibitors were briefly summarized, in order to provide information for the related research.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2023
Tipo del documento:
Artículo
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