Research Progress in the Role of Tamoxifen in Nervous System and Cognitive Function / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 334-340, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-981273
ABSTRACT
Neurological diseases include a variety of neurodegenerative diseases and other brain damage diseases.The treatment schemes for neurological diseases are still in research.The existing clinical and basic studies have confirmed that traditional estrogen therapy has certain protective effect on the nervous system,while it increases the risk of breast or endometrial cancer.The emergence of the selective estrogen receptor modulators (SERMs) can avoid the above mentioned problems.The available studies have confirmed the protective effect of tamoxifen as a SERM on the nervous system.This paper reviews the role and functioning mechanisms of tamoxifen in the nervous system and cognitive function,aiming to provide guidance for the future application of tamoxifen in the treatment of neurological diseases and the improvement of cognitive function.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tamoxifeno
/
Cognición
/
Moduladores Selectivos de los Receptores de Estrógeno
/
Sistema Nervioso
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2023
Tipo del documento:
Artículo
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