Progress of research on the role of Atoh1 gene in the regeneration of mammalian auditory hair cells / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 614-617, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-981799
ABSTRACT
Atoh1 gene encodes a helix-loop-helix transcription factor which is involved in the generation and differentiation of mammalian auditory hair cells and supporting cells, and regulation of the proliferation of cochlear cells, therefore plays an important role in the pathogenesis and recovery of sensorineural deafness. This study reviews the progress of the Atoh1 gene in hair cell regeneration, with the aim of providing a reference for the study of hair cell regeneration gene therapy for sensorineural deafness.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Regeneración
/
Factores de Transcripción
/
Diferenciación Celular
/
Sordera
/
Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico
/
Células Ciliadas Auditivas
/
Pérdida Auditiva Sensorineural
/
Mamíferos
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2023
Tipo del documento:
Artículo
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