Progress of research on chromosomal mosaicism embryos / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 618-623, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-981800
ABSTRACT
Chromosomal mosaicism (CM) is a common phenomenon in preimplantation genetic testing (PGT). In embryos with CM, genetic contents of trophoblastic ectodermal (TE) cells may be different from that of the inner cell mass (ICM) which will develop into the fetus. Embryos with low mosaic proportion could give rise to healthy live births after transplantation, but are accompanied with high pregnancy risks such as high abortion rate. In order to provide a more comprehensive understanding for CM embryos, this article has systematically summarized the recent progress of research on the definition, mechanism, classification, PGT techniques, self-correction mechanism, transplantation outcome and treatment principles for CM embryos.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Blastocisto
/
Pruebas Genéticas
/
Diagnóstico Preimplantación
/
Aneuploidia
/
Mosaicismo
Límite:
Femenino
/
Humanos
/
Embarazo
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2023
Tipo del documento:
Artículo
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