Research updates of C1q/TNF related proteins (CTRPs) in inflammation-related diseases / 细胞与分子免疫学杂志
Chinese Journal of Cellular and Molecular Immunology
;
(12): 649-655, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-981912
ABSTRACT
Inflammation underlies a wide variety of physiological and pathological processes, and plays a pivotal role in controlling pathogen infection. C1q/tumor necrosis factor (TNF) related proteins (CTRPs), a newly discovered adipokine family with conservative structure and wide distribution, has attracted increasing attention. The CTRP family consists of more than 15 members which fall into the characteristic C1q domain. Increasing studies have demonstrated that CTRPs are involved in the onset and development of inflammation and metabolism as well as related diseases, including myocardial infarction, sepsis and tumors. Here, we first clarified the characteristic domains of CTRPs, and then elucidated their roles in inflammatory-related diseases. Taken together, the information presented here provides new perspectives for therapeutic strategies to improve inflammatory and metabolic abnormalities.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Complemento C1q
/
Factor de Necrosis Tumoral alfa
/
Inflamación
/
Infarto del Miocardio
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Cellular and Molecular Immunology
Año:
2023
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS