Research progress on the preparation and application of flavonoid nanocrystals / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 338-348, 2023.
Artículo
en Inglés
| WPRIM
| ID: wpr-982051
ABSTRACT
Flavonoids have been reported to possess significant pharmacological activities,such as antioxidant, anti-inflammatory and anticancer effects. However, the low solubility and low bioavailability limits their clinical application. Nanocrystal technology can solve the delivery problems of flavonoids by reducing particle size, increasing the solubility of insoluble drugs and improving their bioavailability. This article summaries nanosuspension preparation methods and the stabilizers for flavonoid nanocrystals, and reviews the drug delivery routes including oral, Injection and transdermal of flavonoid nanocrystals, to provide information for further research on nanocrystal delivery system of flavonoids.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tamaño de la Partícula
/
Flavonoides
/
Preparaciones Farmacéuticas
/
Disponibilidad Biológica
/
Nanopartículas
/
Antiinflamatorios
Idioma:
Inglés
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2023
Tipo del documento:
Artículo
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