The study on expression of NF-kappaB in experimental brain contusion in rats / 法医学杂志
Journal of Forensic Medicine
;
(6): 73-80, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-983019
ABSTRACT
OBJECTIVE@#To investigate the expression of NF-kappaB in different post-traumatic intervals and severity of brain injury.@*METHODS@#Fifty-four brain tissue samples of slight (n=24), moderate (n=24) brain injury, sham (n=3) and control (n=3) of rat were examined by immunohistochemical staining, westernblot and RT-PCR.@*RESULTS@#Up-regulating of NF-kappaB expression was found in tissues from traumatic brain injury compared with controls in early 1 hour after TBI, and reached peak at 24h and 48h and disappeared after 7 days. The expression of NF-kappaB mRNA has association with contusion severity.@*CONCLUSION@#NF-kappaB may benefit to the estimation of posttraumatic intervals of brain injury.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Coloración y Etiquetado
/
Factores de Tiempo
/
Lesiones Encefálicas
/
ARN Mensajero
/
Inmunohistoquímica
/
Puntaje de Gravedad del Traumatismo
/
Western Blotting
/
FN-kappa B
/
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2004
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS