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Lethal anaphylactic shock model induced by human mixed serum in guinea pigs / 法医学杂志
Journal of Forensic Medicine ; (6): 169-170, 2005.
Artículo en Chino | WPRIM | ID: wpr-983099
ABSTRACT
OBJECTIVE@#To establish an anaphylactic shock model induced by human mixed serum in guinea pigs.@*METHODS@#Eighteen guinea pigs were divided into two groups sensitized and control, The sensitized group were immunized intracutaneously with human mixed serum and then induced by endocardiac injection after 3 weeks.@*RESULTS@#Symptoms of anaphylactic shock appeared in the sensitized group. The level of serum IgE were increased in the sensitized group significantly.@*CONCLUSIONS@#An animal model of anaphylactic shock wer established successfully. It provide a tool for both forensic study and anaphylactic shock therapy.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Inmunoglobulina G / Radioinmunoensayo / Alérgenos / Distribución Aleatoria / Muerte Súbita / Suero / Modelos Animales de Enfermedad / Medicina Legal / Cobayas / Anafilaxia Límite: Animales / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Forensic Medicine Año: 2005 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Inmunoglobulina G / Radioinmunoensayo / Alérgenos / Distribución Aleatoria / Muerte Súbita / Suero / Modelos Animales de Enfermedad / Medicina Legal / Cobayas / Anafilaxia Límite: Animales / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Forensic Medicine Año: 2005 Tipo del documento: Artículo