The expression and significance of IgE in anaphylactic shock guinea-pigs / 法医学杂志
Journal of Forensic Medicine
; (6): 18-20, 2006.
Article
en Zh
| WPRIM
| ID: wpr-983120
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To seek the pathomorphological targets for forensic expertise in anaphylactic shock.@*METHODS@#The expression of IgE in hearts, lungs, livers, spleens, kidneys, gastrics, intestinals, tracheas and tonsils of anaphylactic shock guinea-pigs was observed at 0, 6, 12 h and 24 h respectively by tissue chip S-P immuno-histochemical method.@*RESULTS@#Positive expression of IgE presented in lungs and tracheas in the test group with the peak at 0 hour and it declined as time advanced, and also there were significant differences at different times (P<0.05).@*CONCLUSION@#The immuno-histochemical method of detecting the expression of IgE in lungs, tracheas and spleens can be supposed to be the pathomorphological targets for forensic expertise in anaphylactic shock. The weakening of the positive expression of IgE in lungs and tracheas as the time advanced suggested that in this kind of case the autopsy should be arried out as early as possible.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Cambios Post Mortem
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Bazo
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Factores de Tiempo
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Tráquea
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Inmunoglobulina E
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Inmunohistoquímica
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Alérgenos
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Patologia Forense
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Modelos Animales de Enfermedad
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Cobayas
Límite:
Animals
Idioma:
Zh
Revista:
Journal of Forensic Medicine
Año:
2006
Tipo del documento:
Article