Immunohistochemical study on contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with unknown type of pathological lesion / 法医学杂志
Journal of Forensic Medicine
;
(6): 413-416, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-983236
ABSTRACT
OBJECTIVE@#To investigate the structural characteristics of the cerebral small vessels with an unknown type of pathological lesion (UTPL).@*METHODS@#Contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with UTPL were studied by Congo red staining, immunohistochemical staining and computer image analysis.@*RESULTS@#The low expression levels of alpha-actin and collagen IV (P<0.05) were observed in tunica media of the vessels with UTPL, and no positive expression of beta-amyloid (P>0.05) was observed in these vessel walls. The expressions of proteins mentioned above in UTPL were different from those of cerebral amyloid angiopathy(CAA) and hyaline arteriolosclerosis.@*CONCLUSION@#UTPL was different from CAA or hyaline arteriolosclerosis in pathologic feature.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Autopsia
/
Coloración y Etiquetado
/
Hemorragia Subaracnoidea
/
Vasos Sanguíneos
/
Procesamiento de Imagen Asistido por Computador
/
Encéfalo
/
Inmunohistoquímica
/
Péptidos beta-Amiloides
/
Actinas
/
Angiopatía Amiloide Cerebral
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2006
Tipo del documento:
Artículo
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