Immunohistochemical study on contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with unknown type of pathological lesion / 法医学杂志
Journal of Forensic Medicine
; (6): 413-416, 2006.
Article
en Zh
| WPRIM
| ID: wpr-983236
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the structural characteristics of the cerebral small vessels with an unknown type of pathological lesion (UTPL).@*METHODS@#Contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with UTPL were studied by Congo red staining, immunohistochemical staining and computer image analysis.@*RESULTS@#The low expression levels of alpha-actin and collagen IV (P<0.05) were observed in tunica media of the vessels with UTPL, and no positive expression of beta-amyloid (P>0.05) was observed in these vessel walls. The expressions of proteins mentioned above in UTPL were different from those of cerebral amyloid angiopathy(CAA) and hyaline arteriolosclerosis.@*CONCLUSION@#UTPL was different from CAA or hyaline arteriolosclerosis in pathologic feature.
Texto completo:
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Índice:
WPRIM
Asunto principal:
Autopsia
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Coloración y Etiquetado
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Hemorragia Subaracnoidea
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Vasos Sanguíneos
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Procesamiento de Imagen Asistido por Computador
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Encéfalo
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Inmunohistoquímica
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Péptidos beta-Amiloides
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Actinas
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Angiopatía Amiloide Cerebral
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Forensic Medicine
Año:
2006
Tipo del documento:
Article