Relationship between P300 and intelligence quotient in severe head injury patients / 法医学杂志

ABSTRACT

OBJECTIVE@#To explore the change of brain cognition function in severe head injury and the correlation between P300 in event-related potential (ERP) and intelligence quotient (IQ).@*METHODS@#Auditory P300 was measured and intelligence quotient was tested by Wechsler Adult Intelligence Scale Revised in China (WAIS-RC) in 40 severe head injury patients. Auditory P300 was measured in 40 normal healthy people as control group.@*RESULTS@#The latencies of P300 in severe head injury patients group were longer than in control group. There was a significant difference between the two groups (P< 0.01). There were significant negative correlations between P300 latency and VIQ and FIQ respectively (r=-0.335,-0.344, P<0.05).@*CONCLUSION@#ERP might be taken as an objective index for measuring the change of the brain cognition function in patients with severe head injury.