Distribution of tryptophan hydroxylase gene-T457C locus polymorphism in Han ethnic group in northern China / 法医学杂志
Journal of Forensic Medicine
;
(6): 444-445, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-983337
ABSTRACT
OBJECTIVE@#To study the distribution of the tryptophan hydroxylase (TPH) gene-T457C locus polymorphism in Han ethnic group in northern China and to find its applicable value in forensic science.@*METHODS@#Genomic DNA samples, extracted from 180 unrelated individuals in northern Chinese Han population, were analyzed by PCR-RFLP.@*RESULTS@#The discrimination power (DP) value and the power of exclusion (PE) value of the TPH gene-T457C locus were 0.624 and 0.187, respectively. The allele frequency showed significant difference from that of French people (P=0.04).@*CONCLUSION@#Polymorphism of the TPH gene-T457C locus could show ethnic and regional differences. It has a potential to be used in forensic science.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polimorfismo Genético
/
Triptófano Hidroxilasa
/
China
/
Reacción en Cadena de la Polimerasa
/
Análisis de Secuencia de ADN
/
Pueblo Asiatico
/
Electroforesis en Gel de Poliacrilamida
/
Alelos
/
Frecuencia de los Genes
/
Genotipo
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2007
Tipo del documento:
Artículo
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