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Coma criterion and classification standard of mild and moderate traumatic brain injury in rats / 法医学杂志
Journal of Forensic Medicine ; (6): 8-11, 2008.
Artículo en Chino | WPRIM | ID: wpr-983344
ABSTRACT
OBJECTIVE@#To set up a classification standard of mild and moderate traumatic brain injury, for the purpose of reliable data comparison derived from different laboratories.@*METHODS@#Traumatic brain injury (TBI) in rats was prepared by using a metallic pendulum-striker device. After injury, five variable parameters including the time of apnea and the areflexia, time of corneal reflex, external auditory canal stung reaction, body-righting reflex and needling reaction were determined and scored by using rat coma criterion. These data were judged and classified into mild and moderate head injury by brain patho-anatomy changes. Then the data were used to set up a multivariate discriminate equation.@*RESULTS@#The distinguished probability of mild and moderate TBI according to actual direct measured value and the criterion were 88.9% and 91.9%, respectively.@*CONCLUSION@#This method is able to classify mild and moderate TBI in rats.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Lesiones Encefálicas / Ratas Sprague-Dawley / Coma / Medicina Legal Límite: Animales Idioma: Chino Revista: Journal of Forensic Medicine Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Lesiones Encefálicas / Ratas Sprague-Dawley / Coma / Medicina Legal Límite: Animales Idioma: Chino Revista: Journal of Forensic Medicine Año: 2008 Tipo del documento: Artículo