Distribution of aconitum alkaloids in the corpse died of acute aconite intoxication / 法医学杂志

ABSTRACT

OBJECTIVE@#To investigate the distribution of aconite alkaloids in biological fluids and tissues in the corpse died of acute aconite intoxication and to provide information for sample selection and result evaluation in forensic identification.@*METHODS@#The content of aconite alkaloids in biological fluids and tissues were determined by liquid chromatography-tandem mass spectrometry.@*RESULTS@#The content of aconite displayed in decending order of urine, bile, gastric content, heart blood, pancreas, heart, intestine, liver, kidney, stomach, lung, gallbladder and spleen, with no aconite detected in the brain.@*CONCLUSION@#It was indicated that urine, bile and blood are the best specimens for the determination of aconite in body of the acute aconite intoxication.