Advancement of methanol poisoning mechanism research / 法医学杂志
Journal of Forensic Medicine
;
(6): 294-296, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-983585
ABSTRACT
The methanol poisoning by oral intake or skin contact occurs occasionally, which may have serious consequences including blindness and/or death. Methanol and its metabolites, formaldehyde and formic acid, are associated with metabolic acidosis, visual dysfunction and neurological symptoms. At present, the mechanism of methanol poisoning primarily focuses on the cell hypoxia, the alteration of structure and biological activity induced by free radical and lactic acid. Meanwhile, methanol poisoning causes changes in the balance between the production of free radicals and antioxidant capacity and in the proteases-protease inhibitors system, which lead to a series of disturbances.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Acidosis
/
Trastornos de la Visión
/
Proteínas
/
Metanol
/
Formaldehído
/
Formiatos
/
Radicales Libres
/
Oxidorreductasas actuantes sobre Donantes de Grupo CH-NH
/
Sistema Nervioso
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2010
Tipo del documento:
Artículo
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