Application of liquid chromatography-high resolution mass spectrometry in toxicological screening / 法医学杂志
Journal of Forensic Medicine
;
(6): 376-381, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-983686
ABSTRACT
Due to the diversity of toxicologically relevant substances, the uncertainty of target compounds and the specificity of samples, toxicological screening techniques have always been valued by the forensic toxicologists. Depending on its powerful separation ability, superhigh resolution and accurate mass measurement, combined with the two levels spectrum database matching and abundance ratio of isotope ion, the liquid chromatography-high resolution mass spectrometry (LC-HRMS) analyzers have increasingly advantage in screening and identification of chemical compound. This review focuses on the applications of LC-HRMS in screening and identification of drug-of-abuse, prescription drugs, pesticide and stimulant. The prospect of LC-HRMS in forensic toxicology analysis is also included.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Plaguicidas
/
Residuos de Plaguicidas
/
Detección de Abuso de Sustancias
/
Fármacos del Sistema Nervioso Central
/
Cromatografía Liquida
/
Sensibilidad y Especificidad
/
Pruebas de Toxicidad
/
Doping en los Deportes
/
Espectrometría de Masas en Tándem
/
Toxicología Forense
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2011
Tipo del documento:
Artículo
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