Progress on epigenetics applications in forensic science / 法医学杂志
Journal of Forensic Medicine
;
(6): 366-370, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-983764
ABSTRACT
Epigenetics is the study of heritable changes in gene expression other than changes in the underlying DNA sequence. Such changes include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, X chromosome inactivation and non-coding RNA regulation. Recent progresses on epigenetics open new possibilities in tackling these challenging problems in forensic science, including identification of fetal paternity testing in embryonic period, determination of the necessary allele in paternity testing, discrimination of identical twins, origination analysis of micro tissue, verification of forged DNA. This review focuses on epigenetics concept and its latest application in the field of paternity testing, age estimation, discrimination between the twins, identification of tissue of origin, and estimation of postmortem interval.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Gemelos Monocigóticos
/
Expresión Génica
/
Impresión Genómica
/
Metilación de ADN
/
Epigénesis Genética
/
Ciencias Forenses
/
Alelos
/
Epigenómica
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2012
Tipo del documento:
Artículo
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