Research Progress of the Relationship between the Expression of TAR DNA-binding Domain Protein 43 and Brain Injury / 法医学杂志
Journal of Forensic Medicine
;
(6): 289-292, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-984895
ABSTRACT
TAR DNA-binding domain protein 43 (TDP-43) is a highly conserved and widely expressed nuclear protein. Nowadays, the expression of TDP-43 can be found in most neurodegenerative diseases such as Alzheimer's disease, which makes it become a neurodegenerative disease associated marker protein. From the current research status at homeland and abroad, and around the relationship between the expression of TDP-43 and brain injury, this article emphatically probes into the specific expression and function of TDP-43 in acute and chronic brain injury based on the knowledge of its biological characteristics, which aims to explore the feasibility for determining the cause of death and the injury and disability situations by TDP-43 in forensic pathology.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Lesiones Encefálicas
/
ADN
/
Proteínas de Unión al ADN
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Forensic Medicine
Año:
2017
Tipo del documento:
Artículo
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