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Research Progress of Metabolomics in Forensic Pathology / 法医学杂志
Journal of Forensic Medicine ; (6): 347-353, 2020.
Artículo en Inglés | WPRIM | ID: wpr-985124
ABSTRACT
Metabolomics is an interdisciplinary subject that rose in the post-genomic era, which focuses on quantitative study of the response of living organisms to outside stimulation and pathophysiological changes, as well as multiple dynamic response of the level of in vivo metabolites caused by genetic mutation. It is extensively used in basic research of system biology, materia medica, clinical medicine, etc. In the forensic field, metabolomics mainly focuses on forensic toxicology, but with the generalization of certain techniques, it's foreseeable that metabolomics has a broad research prospect in forensic pathology. This article summarizes the major analysis techniques and methods of metabolomics, describes the research status of metabolomic techniques in the field of forensic pathology application research, including postmortem interval and death cause. Moreover, this article summarizes and discusses the potential applicable areas, in order to provide reference for relative research and application.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cambios Post Mortem / Autopsia / Patologia Forense / Toxicología Forense / Metabolómica Límite: Humanos Idioma: Inglés Revista: Journal of Forensic Medicine Año: 2020 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Cambios Post Mortem / Autopsia / Patologia Forense / Toxicología Forense / Metabolómica Límite: Humanos Idioma: Inglés Revista: Journal of Forensic Medicine Año: 2020 Tipo del documento: Artículo