Forensic Application of Next Generation Sequencing Technology in the Typing of Y Chromosome Genetic Markers / 法医学杂志
Journal of Forensic Medicine
;
(6): 91-98, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-985200
ABSTRACT
The paternal inheritance characteristics of Y chromosome have been widely used in the forensic genetics field to detect the genetic markers in the non-recombining block, and used in the studies such as, genetic relationship identification, mixed stain detection, pedigree screen and ethnicity determination. At present, capillary electrophoresis is still the most common detection technology. The commercial detection kits and data analysis and processing system based on this technology are very mature. However, the disadvantages of traditional detection technology have gradually appeared with the rapid growth of bio-information amount, which promotes the renewal of forensic DNA typing technology. In recent years, next generation sequencing (NGS) technology has developed rapidly. This technology has been applied to various fields including forensic genetics and has provided new techniques for the detection of Y chromosome genetic markers. This article describes the current situation and application prospects of the NGS technology in forensic Y chromosome genetic markers detection in order to provide new ideas for future judicial practice.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tecnología
/
Cromosoma Y
/
Marcadores Genéticos
/
Dermatoglifia del ADN
/
Repeticiones de Microsatélite
/
Cromosomas Humanos Y
/
Genética Forense
/
Secuenciación de Nucleótidos de Alto Rendimiento
Límite:
Humanos
Idioma:
Inglés
Revista:
Journal of Forensic Medicine
Año:
2021
Tipo del documento:
Artículo
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