Constructions and advances of animal models of Pseudomonas aeruginosa infection / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 929-934, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-985498
ABSTRACT
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogenic bacterium with complex pathogenesis and drug resistance mechanisms. It has high morbidity and mortality and can cause acute and chronic infections in immunocompromised individuals, with lung infections, wound infections, and bloodstream infections being the most common. The animal infection model of P. aeruginosa is of great value for in-depth research on the pathogenicity, drug resistance, and therapeutic measures of P. aeruginosa by simulating the pathways of human bacterial infections. This article firstly summarizes the selection, anesthesia, and disposal of experimental animals in the construction of animal models of P. aeruginosa infection, and then reviews the methods of construction, model evaluation, and applications of animal models of P. aeruginosa pulmonary infection, wound infection, and bloodstream infection, in order to provide a reference for scientific research related to P. aeruginosa infectious diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pseudomonas aeruginosa
/
Infecciones por Pseudomonas
/
Virulencia
/
Modelos Animales
/
Modelos Animales de Enfermedad
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Preventive Medicine
Año:
2023
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS