Advances in Combined Immunotherapy for Triple Negative Breast Cancer / 肿瘤防治研究
Cancer Research on Prevention and Treatment
; (12): 996-1002, 2022.
Article
en Zh
| WPRIM
| ID: wpr-986619
Biblioteca responsable:
WPRO
ABSTRACT
The triple-negative breast cancer has a relatively poor prognosis with limited therapeutic options. This subtype is highly immunogenetic and exhibits rich tumor infiltrated lymphocytes in the tumor microenvironment. However, immunotherapy alone is less effective as compared with the doublet of chemotherapy and immunotherapy in TNBC. The efficacy in early recurrence settings of mTNBC exceeds that in heavily treated subgroups. Meanwhile, other combinations including anti-angiogenesis, immune modulators, and PARPi elicit a promising effect. Herein, this paper reviews the progress of efficacy, safety, and the outlook in the immunotherapy of TNBC disease.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Cancer Research on Prevention and Treatment
Año:
2022
Tipo del documento:
Article