Research progress of the screening and generation of lead compounds based on artificial intelligence model / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 294-304, 2023.
Article
en Zh
| WPRIM
| ID: wpr-987645
Biblioteca responsable:
WPRO
ABSTRACT
@#Excellent lead compounds have a profound influence on drug development and can improve the success rate of product launch. It is expensive and time-consuming to discover lead compounds by traditional methods, yet artificial intelligence (AI) can discover good lead compounds efficiently.This article systematically summarizes the research progress of obtaining lead compounds through the screening and generation models of AI, classifies different models according to the type of information input, focuses on drug repurposing by screening model and multi-objective drug design by generation model, and discusses the development prospect of AI in the research field of lead compounds, aiming to provide new research ideas for the application of AI in lead compounds.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of China Pharmaceutical University
Año:
2023
Tipo del documento:
Article