Your browser doesn't support javascript.
loading
Research progress on analgesic effect and adverse drug reactions of opioid receptor agonist-antagonists / 中国药房
China Pharmacy ; (12): 2299-2304, 2023.
Artículo en Chino | WPRIM | ID: wpr-988795
ABSTRACT
Opioid receptor agonist-antagonists are a class of drugs which have both agonistic and antagonistic effects on opioid receptors. These drugs already on the market mainly include pentazocinebutorphanolnalbuphinebuprenorphine, dezocine and so on. Compared with pure opioid receptor agonists such as morphine and fentanyl, these drugs have strong analgesic effects, less addictive, and less side effects such as coughitching and respiratory depression. Due to the different tendentious effects of opioid receptor agonists-antagonists among different endogenous opioid receptors (μ, κ, δ, etc.), different receptors of subtypes can exhibit different or even opposite effects in terms of affecting emotions and drug dependence. Therefore, the rational use of these drugs can effectively reduce the occurrence of adverse reactions and drug abuse caused by opioid drugs. With the deepening of research on various endogenous opioid receptor subtypes and related drugs in the academic communityopioid receptor agonists- antagonists have broad application space and prospects in improving adverse reactions to opioid drugs and enhancing patient drug compliance.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Pharmacy Año: 2023 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: China Pharmacy Año: 2023 Tipo del documento: Artículo