Research progress on the skeletal muscle mitochondrial alterations and the treatment in cancer cachexia / 中华临床营养杂志
Chinese Journal of Clinical Nutrition
;
(6): 117-122, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-991918
ABSTRACT
Cancer cachexia is a multifactorial syndrome characterized by the continuous loss of skeletal muscle. The pathogenic mechanism of cancer cachexia remains unknown, and the effectiveness of routine nutritional therapy is limited. The mitochondrial disorder is demonstrated to play an important role in the mechanism of tumor-induced skeletal muscle atrophy, including alterations to the mitochondrial ultrastructure, biogenesis, dynamics, mitophagy, and functions. Interventions targeting mitochondrial alterations provide a potential solution to cancer cachexia and represent a new focus in this research field.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Clinical Nutrition
Año:
2023
Tipo del documento:
Artículo
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